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Bengaluru, May 14, 2013 /PRNewswire/ -- Rupri Pharma, Ltd., a wholly owned subsidiary of Ranbaxy Laboratories Ltd., today announced it has received regulatory approval for the commercialization of the anti-impotence drug Viagra (sildenafil citrate).

The company, which is based in Kota, Japan, is currently marketing a generic version of the erectile dysfunction drug Viagra (sildenafil citrate) in the country, according to Rupri Pharma's press release.

"We are very pleased to introduce Rupri Pharma to the world, and we are confident that we will be able to commercialize this innovative medication in many other countries around the world," said Sildenafil Citrate's head, Rajeev Narula, Chairman and Chief Executive Officer (CEO) of Rupri Pharma. "The successful launch of the generic version of Viagra in the country, together with the quality and safety of the drug in the country, is a major positive for Rupri and our global portfolio of innovative medicines, including Viagra, which is currently approved in several European countries."

Viagra is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). cGMP, which is composed of cyclic guanosine monophosphate and is the main molecule in penile blood vessels, is responsible for producing the erectile response.

Rupri is currently working on a new drug application for this product which is expected to launch in the next two years.

"We have always taken a keen interest in pharmaceuticals and had a clear vision to develop a new therapeutic approach for erectile dysfunction," said Rajeev Narula, Chairman and Chief Executive Officer of Rupri Pharma. "Our first priority is to market our generic version of Viagra and make it available in all European countries. Our vision is to become one of the most trusted brands in the world. We are very pleased that our company has received regulatory approval to commercialize this drug. We believe that the commercialization of Viagra will help to expand our portfolio of innovative medicines and make it more accessible to a wider population."

The generic version of Viagra is currently being manufactured and marketed in more than 150 countries including Japan, South Africa, Australia, and United Arab Emirates. Rupri Pharma is based in Kota, Japan.

"Rupri Pharma is very pleased to announce that its generic Viagra product, which has a very promising market prospects for us, will be launched in the first half of 2014," said Sildenafil Citrate's CEO, Narula. "We have been in the market for many years and have always been trusted as one of the best generic drugs in the world. We are very proud of our success in bringing about the growth of the generic Viagra in the pharmaceutical industry and we are very confident that this generic version will have a positive impact on the market and will become one of the best medicines in the world."

Rupri Pharma's global sales for the year ended 31st September 2013 were estimated at about USD 31.3 billion, or 37.7% of total sales for the year ended 31st September 2012.

Rupri Pharma is a subsidiary of Ranbaxy Laboratories Ltd., a wholly owned subsidiary of Ranbaxy Laboratories Ltd., a wholly owned subsidiary of Lilly India Limited. The company is based in Kota, Japan.

Rupri Pharmaceuticals Ltd. is engaged in manufacturing, supplying and marketing of generic drugs in more than 150 countries and territories. The company operates on a global scale, supplying medicines to the world's most urgent need. As of September 2016, the company's turnover was around US$ 2.1 billion.

Rupri is a wholly owned subsidiary of Ranbaxy Laboratories Ltd., a wholly owned subsidiary of Lilly India Limited.

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The Portuguese are seeking for a reason to protect themselves from the side effects of Viagra, according to a study published by researchers in theJournal of Sexual Medicine. The study, which was presented at the European Congress on Monday, was published Monday in theJournal of Sexual Medicine.It shows that men who take Viagra have a higher rate of sexual dysfunction, and that the side effects of Viagra can be more severe. The men in the study were also tested for other sexually transmitted diseases and had a higher rate of genital herpes and other sexually transmitted diseases than men who were not treated with the drug. Viagra and other erectile dysfunction drugs may have other side effects.

In addition, some of the study's findings suggest that the men who took Viagra may be more susceptible to side effects of Viagra, such as headaches, dizziness and fatigue. Viagra is also not recommended for the treatment of impotence, a condition that affects women and people who are of childbearing age. Viagra also is not recommended for the treatment of pulmonary arterial hypertension, a condition in which high blood pressure in the lungs causes chest pain and angina. Viagra is not recommended for the treatment of erectile dysfunction. Viagra is also not recommended for the treatment of pulmonary arterial hypertension, a condition in which high blood pressure in the lungs causes chest pain and angina.

The study was funded by the Spanish Government Agency for Health, Industry and the Public Health Department (AHPIV), a government-funded ministry in the region that is responsible for health and the administration of medicines. AHPIV is responsible for monitoring the situation of health, and distributing its data to medical doctors and other health care professionals. The study is part of a project to investigate the problem of sexual dysfunction in men who have been treated with Viagra and to assess the long-term safety and efficacy of the drug.

Dr. Diego Costa, a researcher at the University of Campinas, said that the study's findings could have a positive impact on the pharmaceutical industry.

"The current situation is very complex. Viagra is not only a drug used to treat erectile dysfunction but also a drug used to treat sexual dysfunction, and there is a risk of having sexual dysfunction if you take Viagra, if you are taking any form of medicine that can cause impotence, and if you have had problems with any form of sexual dysfunction," he said. "However, the research is in the context of the pharmaceutical industry and we have not yet seen any evidence that Viagra could cause sexual dysfunction in men who are taking any form of medicine, and we have seen some studies on the use of Viagra in men who have had problems with sexual dysfunction, but in the general population."

Diego Costa is director of the Spanish Center for Research on Sexual Medicine and is a member of the board of directors of the Spanish Sexual Medicine Society.

VIDEO

This study is published inThe study was published in the

This article originally appeared onSexual Medicine.Copyright © 2021

This content is written in English. All rights reserved.Overturning the fight against sexual dysfunction

If you're experiencing sexual dysfunction, it's important to let your doctor know.

Your health care provider may have prescribed this medication for you. It may also help you to manage your symptoms, such as anxiety, dizziness, headaches, difficulty sleeping, irritability, emotional stress, mood changes, or any other sexual problems.

Erectile dysfunction can be a very distressing condition, so it can be challenging to talk about. But understanding your condition and your options can help make a decision about your treatment. Your doctor can discuss any symptoms you may have and provide advice on how to proceed if you are prescribed this medication.

Viagra (sildenafil) can increase the risk of blood clots in the lungs, according to a study published inIt could also cause an increased risk of heart disease and stroke. In addition, taking Viagra may increase the risk of developing a form of prostate cancer. The study was presented at the European Congress on Sexual Medicine in June 2022.

Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.

Dosage and Administration

Sildenafil is available in 25mg, 50mg, and 100mg strengths.

  • The usual starting dose is 50mg, taken approximately one hour before sexual activity.
  • Dosage can be adjusted depending on individual response and tolerability.
  • Take only one tablet in 24 hours, with or without food.
  • Avoid grapefruit juice, as it can increase the risk of side effects.
  • A high-fat meal may delay onset of action.

Effectiveness

Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.

Side Effects

Common side effects include:

  • Headache
  • Flushing
  • Nasal congestion
  • Indigestion

Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.

Contraindications

Sildenafil should not be used by those:

  • Taking nitrates for chest pain
  • With severe heart or liver conditions
  • Under 18 years of age
  • With certain medication interactions (e.g. alpha-blockers, antifungals, antibiotics)

Interactions

Inform your doctor of all medications and supplements before use. Interactions may occur with:

  • Nitrates
  • Alpha-blockers
  • Some antibiotics and antifungal medicines

Alcohol and Heart Conditions

Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.

Availability and Cost

Sildenafil is available by prescription only in the UK.

  • Generic versions are more affordable than branded Viagra.
  • Supplied by licensed UK pharmacies such as Online Chemist.
  • Avoid counterfeit products from unregulated websites.

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Citation

A. J. K., J. K. F. and S. C. (2010) "Efficacy of Sildenafil (Viagra) in the treatment of erectile dysfunction"Journal of the American Urological Association29: 8-19.

() J. ()

Abstract:

Sildenafil (Viagra) was a commonly prescribed medication used to treat erectile dysfunction. This review examines the efficacy of sildenafil in the treatment of erectile dysfunction in men with ED.

Keywords:

Sildenafil (Viagra):Treatment of ED (erectile dysfunction).

MeSH Cite:This study included 60 men with ED (mean age, 67.2 years; SD: 8.7; range: 18-88 years). The average duration of erectile dysfunction was 12.2 minutes (SD: 5.9 minutes) and of mild ED was 3.6 minutes (SD: 1.8 minutes). The patients were randomized to receive sildenafil (Viagra) or placebo, with or without concomitant therapy. The effect of sildenafil was not statistically significant. The patients who received sildenafil had lower rates of sexual intercourse compared to the placebo group (30.9% vs. 41.2%; P =.05). There was no significant difference between the groups in the time of sexual intercourse.